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To take control of the Side effects

The 6-step TARGET strategy is a step-by-step guide to master side effects effectively & becoming successful in avoiding unnecessary treatment adjustments.

How it Works

From labeling the side effect till the treatment of the side effect: you can walk through the entire process by yourself and this way, for most of the side effects – especially when approached at an early stage - you can control side effects without prescription drugs.

The 6 practical steps

step 1




Assessing signs and symptoms of the adverse event and the impact of an adverse event for a particular patient is crucial to identify the intervention direction.



Reporting of characteristics of the adverse event subtype tells in detail where to look for an appropriate intervention.

step 4


There are much better grading tools available than the CTCAE which will guide you to the best treatment option for a particular adverse event subtype.



If you are on the right path with your measures or if you are approaching the wrong target will become clear in the 5th step.

step 6


Tackling adverse events becomes the easiest step in adverse event management, when you have applied the previous steps.

Success Stories
Patients tell about Christine’s adverse event approach

MS. de Koning:

I developed 90% of the adverse events that can come along with panitumumab. With help of the TARGET strategy I was able to relieve the adverse events within 48 hours every time. Even the nail of this finger was not removed at the emergency room because it was treated effectively with vinegar bathes supported with antibiotics. Simple, effective and fast!

MR. Stipdonk:

I suffered calluses my entire life, but the calluses grew exponentially large while on regorafenib. I was not able to walk anymore or enjoy my hobby. Christine explained how to apply the TARGET strategy on the calluses and how I could get rid of them. I followed the strategy and you can see the result: I am still on regorafenib AND can enjoy my hobby again. The TARGET strategy led to hemorrhoid cream. Amazing what hemorrhoid cream on the hand palms and foot soles can do!

MR. Schultze: 

My mother was diagnosed with NSCLC in September 2012 and treated with gefitinib. She wanted to stop treatment due to extremely painful nail folds. 

Through Christine’s simple, but effective measures, resulting from the TARGET strategy, my mother was able to continue treatment for
 5 more years!

Results Don’t Happen On Accident.

STRUCTURE Gives You Results.

From Indecision to Tackled Adverse Events in 6 Steps


Learn about Christine's proven 6-Step TARGET Strategy about how to control adverse events effectively.

Apply these basic principles on the prescription drugs you work with and see results immediately.

When you apply the 6 TARGET Steps on an adverse event:

  • Prescription drugs will lead to less symptom burden.
  • It becomes easier for you to distinguish adverse events for instance between cytotoxic chemotherapy and targeted therapy.
  • You will be able to limit adverse events of systemic therapies.
  • The scope of the adverse events becomes more apparent to you.
  • You will be able to select appropriate management options according to the adverse event subtype.
  • You will be able to promote compliance with the needed therapy.
  • You will be able to avoid unnecessary treatment discontinuation or dose adjustments.

Results don't happen on accident.

What Key Opinion Leaders say about The TARGET Strategy:

It's a Key Tool!

“The six steps in The Target Strategy are very helpful in a busy clinical setting or during research protocols."

Mario E. Lacouture, MD

Dermatology Service

Department of Medicine

Memorial Sloan-Kettering Cancer Center (MSKCC),

New York, USA

Promotes Continuation of Therapy!
"Chris is very dedicated in improving a patients’ quality of life by finding solutions for every patient."

Joel B. Epstein, DMD

American Board of Oral Medicine Collaborative Member, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA &

Division of Otolaryngology & Head & Neck Surgery, City of Hope, Duarte, CA, USA

It's a Unique,

Practical Tool!

"The six steps can be very helpful to manage complicated side effects, and it is more likely that the entire extent is explored and treated in the right way.”

Erik van Muilekom, MANP

Antoni van Leeuwenhoek (AVL) Hospital

Netherlands Cancer Institute (NKI)

Amsterdam, The Netherlands

& Past -president of EONS

Six Practical Steps.

From diagnosis to management of side effects

As a researcher, coach, and author I help professionals who work with prescription drugs to improve treatment skills related to adverse events with special attention to immuno-oncology & targeted therapy in cancer.

Since 2006 I teach this approach globally.

I help professionals who work with prescription drugs and their team how to apply The TARGET System in daily practice and achieve better patient outcomes.

I write articles about the different adverse event subtypes and how to approach them systematically. In August 2014 my book The TARGET System was published.

Unleash the potential of prescription drugs,

Christine Boers-Doets

The Cost of Not Using the TARGET Strategy...

There is nothing more frustrating and killing for your day-to-day practice as struggling with the Not-Taking-Cancer-Medication-As-Planned to execute your plans. As an Adverse Event Master I know exactly how it feels like no one else, and therefore I developed The TARGET System for my own use.

Tell me, how much is it worth to you to miss out on success from untreated adverse events?

Tailor my experience